About the Authors

Kristin Lees

Contributed equally to this work with: Kristin Lees, Maria Musgaard

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Maria Musgaard

Contributed equally to this work with: Kristin Lees, Maria Musgaard

Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Siros Suwanmanee

Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom

Steven David Buckingham

Affiliation Wolfson Institute for Biomedical Research, Department of Medicine, University College London, London, United Kingdom

Philip Biggin

Affiliation Department of Biochemistry, University of Oxford, Oxford, United Kingdom

David Sattelle

d.sattelle@ucl.ac.uk

Affiliation Wolfson Institute for Biomedical Research, Department of Medicine, University College London, London, United Kingdom

Competing Interests

This work was supported by Merial Ltd, via a post-doctoral grant to DBS supporting KL. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PB DS SDB. Performed the experiments: KL MM SS. Analyzed the data: PB SDB. Wrote the paper: KL SDB DS.