About the Authors

Ana Töpf

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Helen R. Griffin

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Elise Glen

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Rachel Soemedi

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Danielle L. Brown

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Darroch Hall

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Thahira J. Rahman

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Jyrki J. Eloranta

Affiliation Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland

Christoph Jüngst

Affiliations Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland, Department of Medicine II, Saarland University Medical Center, Homburg, Germany

A. Graham Stuart

Affiliation Bristol Royal Hospital for Children, Bristol, United Kingdom

John O'Sullivan

Affiliation Paediatric Cardiology, Freeman Hospital Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom

Bernard D. Keavney

judith.goodship@ncl.ac.uk (BDK); bernard.keavney@manchester.ac.uk (JAG)

Affiliations Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, Institute of Cardiovascular Sciences, The University of Manchester, Manchester, United Kingdom

Judith A. Goodship

judith.goodship@ncl.ac.uk (BDK); bernard.keavney@manchester.ac.uk (JAG)

Affiliation Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AT HRG JO AGS BDK JAG. Performed the experiments: AT HRG EG RS DH TJR CJ. Analyzed the data: AT HRG EG RS DLB DH. Contributed reagents/materials/analysis tools: JJE AGS JO. Wrote the paper: AT JAG BDK.