About the Authors

Thorsten Fuereder

Affiliation Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Volker Wacheck

Affiliation Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

Sabine Strommer

Affiliation Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

Peter Horak

Affiliation Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Marion Gerschpacher

Affiliation Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Wolfgang Lamm

Affiliation Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Danijel Kivaranovic

Affiliation Section for Medical Statistics, Medical University of Vienna, Vienna, Austria

Michael Krainer

michael.krainer@meduniwien.ac.at

Affiliation Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria

Competing Interests

Pfizer Corpporation and Sanofi, who funded this study by an unrestricted research grant, as competing interest. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TF SS VW MK WL PH MG. Performed the experiments: TF SS. Analyzed the data: TF VW MK WL MG PH DK. Contributed reagents/materials/analysis tools: MK VW. Wrote the paper: TF VW MK WL MG PH DK.