About the Authors

Lukas E. Dow

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Zeina Nasr

Affiliation Department of Biochemistry, McGill University, Montreal, Quebec, Canada

Michael Saborowski

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Saya H. Ebbesen

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Eusebio Manchado

Affiliation Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Nilgun Tasdemir

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Teresa Lee

Affiliation Department of Biochemistry, McGill University, Montreal, Quebec, Canada

Jerry Pelletier

jerry.pelletier@mcgill.ca (JP); lowes@mskcc.org (SWL)

Affiliations Department of Biochemistry, McGill University, Montreal, Quebec, Canada, The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec, Canada

Scott W. Lowe

jerry.pelletier@mcgill.ca (JP); lowes@mskcc.org (SWL)

Affiliations Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

Competing Interests

SWL and LED are members of the Scientific Advisory Board and hold equity in Mirimus Inc., a company that has licensed some of the technology reported in this manuscript. The authors' involvement in Mirimus Inc. (LED and SWL) does not alter their adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LED ZN MS SHE NT JP SWL. Performed the experiments: LED ZN MS SHE EM NT TL JP. Analyzed the data: LED ZN JP. Contributed reagents/materials/analysis tools: LED MS SHE TL JP. Wrote the paper: LED JP SWL.