About the Authors

Megumi Matsumoto

matsumegrace@gmail.com

Affiliation Department of Physical Education, College of Humanities and Sciences, Nihon University, 3-25-40, Sakurajosui, Setagaya-ku, Tokyo, Japan

Masahito Hagio

Affiliations Research Faculty of Agriculture, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo, Hokkaido, Japan, Faculty of Life Sciences, Toyo University, 1-1-1 Izumino, Itakura-machi, Ora-gun, Gunma, Japan

Ryo Inoue

Affiliation Laboratory of Animal Science, Kyoto Prefectural University, Shimogamo, Kyoto, Japan

Tomohiro Mitani

Affiliation Research Faculty of Agriculture, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo, Hokkaido, Japan

Masako Yajima

Affiliation Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, Hokkaido, Japan

Hiroshi Hara

Affiliation Research Faculty of Agriculture, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo, Hokkaido, Japan

Takaji Yajima

Affiliation Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, Hokkaido, Japan

Competing Interests

The authors received funding from a commercial source “Meiji Co.” The authors declare that this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MM MH HH TY. Performed the experiments: MM MH RI TM. Analyzed the data: MM MH. Contributed reagents/materials/analysis tools: MM RI TM MY HH. Wrote the paper: MM MH.