About the Authors

Saad Yousuf

Contributed equally to this work with: Saad Yousuf, MeiLi Duan

Affiliation Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

MeiLi Duan

Contributed equally to this work with: Saad Yousuf, MeiLi Duan

Affiliations Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America, Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China

Erika L. Moen

Affiliation Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Sam Cross-Knorr

Affiliation Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Kate Brilliant

Affiliation Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Benjamin Bonavida

Affiliation Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, California, United States of America

Theresa LaValle

Affiliation Kolltan Pharmaceuticals, Inc., New Haven, Connecticut, United States of America

Kam C. Yeung

Affiliation Department of Biochemistry and Cancer Biology, University of Toledo, College of Medicine, Toledo, Ohio, United States of America

Fahd Al-Mulla

Affiliation Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait

Eugene Chin

Affiliation Department of Surgical Research, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Devasis Chatterjee

Devasis_Chatterjee@brown.edu

Affiliation Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Competing Interests

The authors declare that previous affiliation to MedImmune and current affiliation to Kolltan, Inc. does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DC EC KCY. Performed the experiments: DC SY MD ELM SC-K KB. Analyzed the data: DC SY ELM SK-C KB KCY EC. Contributed reagents/materials/analysis tools: KY BB TL EC. Wrote the paper: DC EC BB FA.