About the Authors

Sudhir Varma

Affiliations Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, HiThru Analytics LLC, Laurel, Maryland, United States of America

Yves Pommier

wcr@mail.nih.gov (WCR); pommier@nih.gov (YP)

Affiliation Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Margot Sunshine

Affiliations Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Systems Research and Applications Corporation, Fairfax, Virginia, United States of America

John N. Weinstein

Affiliation Departments of Bioinformatics and Computational Biology and Department of Systems Biology, M.D. Anderson Cancer Center, Houston, Texas, United States of America

William C. Reinhold

wcr@mail.nih.gov (WCR); pommier@nih.gov (YP)

Affiliation Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

Sudhir Varma is an employee of HiThru Analytics LLC working under contract to the NCI providing bioinformatics and computational services. He has no other commercial interest in the research published in this article. Margot Sunshine is an employee of Systems Research and Applications (SRA) working under contract to the NCI, providing computational and web development services. She has no other commercial interest in the research published in this article. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SV WCR JNW. Performed the experiments: WCR. Analyzed the data: SV. Wrote the paper: SV WCR MS YP JNW. Database and website development: MS SV.