About the Authors

Katsuya Morita

Contributed equally to this work with: Katsuya Morita, Seiji Shiraishi, Naoyo Motoyama

Affiliations Department of Pharmacology, Faculty of Nursing, Hiroshima Bunka Gakuen University, Hiroshima, Japan, Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan, Department of Cell and Molecular Pharmacology, Division of Basic Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

Seiji Shiraishi

Contributed equally to this work with: Katsuya Morita, Seiji Shiraishi, Naoyo Motoyama

Affiliation Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan

Naoyo Motoyama

Contributed equally to this work with: Katsuya Morita, Seiji Shiraishi, Naoyo Motoyama

Affiliations Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan, Department of Dental Science for Health Promotion, Division of Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

Tomoya Kitayama

Affiliation Department of Cell and Molecular Pharmacology, Division of Basic Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

Takashi Kanematsu

Affiliation Department of Cell and Molecular Pharmacology, Division of Basic Life Science, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

Yasuhito Uezono

Affiliation Cancer Pathophysiology, Division National Cancer Center Research Institute, Tokyo, Japan

Toshihiro Dohi

t-dohi@nichiyaku.ac.jp

Affiliation Department of Pharmacotherapy, Pharmaceutical Sciences, Nihon Pharmaceutical University, Saitama, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KM TD NM SS. Performed the experiments: KM NM T. Kitayama SS. Analyzed the data: KM NM T. Kanamatsu SS YU. Contributed reagents/materials/analysis tools: NM KM T. Kanematsu. Wrote the paper: TD KM NM.