About the Authors

Tomonori Kimura

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Eizo Watanabe

watanabee@faculty.chiba-u.jp

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Teruo Sakamoto

Affiliation Department of Emergency and Critical Care Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume City, Fukuoka, Japan

Osamu Takasu

Affiliation Department of Emergency and Critical Care Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume City, Fukuoka, Japan

Toshiaki Ikeda

Affiliation Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center, 1163 Tate-machi, Hachioji City, Tokyo, Japan

Kazumi Ikeda

Affiliation Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center, 1163 Tate-machi, Hachioji City, Tokyo, Japan

Joji Kotani

Affiliation Department of Emergency, Disaster and Critical Care Medicine, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya City, Hyogo, Japan

Nobuya Kitamura

Affiliation Department of Emergency and Critical Care Medicine, Kimitsu Chuo Hospital, 1010 Sakurai, Kisarazu City, Chiba, Japan

Tomohito Sadahiro

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Yoshihisa Tateishi

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Koichiro Shinozaki

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Shigeto Oda

Affiliation Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chu-ku, Chiba City, Chiba, Japan

Competing Interests

ZENKYOREN provided funding towards this study (EW). There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EW SO. Performed the experiments: TK. Analyzed the data: TK EW T. Sadahiro YT KS. Contributed reagents/materials/analysis tools: T. Sakamoto OT TI KI JK NK. Wrote the paper: TK EW.