About the Authors

Mary E. Enama

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Julie E. Ledgerwood

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Laura Novik

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Martha C. Nason

Affiliation Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Ingelise J. Gordon

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

LaSonji Holman

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Robert T. Bailer

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Mario Roederer

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Richard A. Koup

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

John R. Mascola

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Gary J. Nabel

Current address: Sanofi-Pasteur, Cambridge, Massachusetts, United States of America

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Barney S. Graham

bgraham@nih.gov

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

the VRC 011 Study Team

Membership of the VRC 011 Study Team is provided in the Acknowledgments.

Competing Interests

Gary J. Nabel is named on patent applications for this vaccine concept.

Author Contributions

Conceived and designed the experiments: BSG MEE MCN JEL. Performed the experiments: BSG JEL IJG LH LN JRM RTB MR RAK GJN. Analyzed the data: BSG MCN MEE RAK GJN. Contributed reagents/materials/analysis tools: JRM RTB MR RAK GJN. Wrote the paper: MEE BSG MCN JEL.