About the Authors

Abrey J. Yeo

Affiliations QIMR Berghofer Medical Research Institute, Radiation Biology and Oncology Laboratory, Brisbane, Queensland, Australia, School of Medicine, University of Queensland, Herston, Queensland, Australia

Olivier J. Becherel

Affiliations QIMR Berghofer Medical Research Institute, Radiation Biology and Oncology Laboratory, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biology, University of Queensland, St. Lucia, Queensland, Australia

John E. Luff

Affiliation QIMR Berghofer Medical Research Institute, Radiation Biology and Oncology Laboratory, Brisbane, Queensland, Australia

Jason K. Cullen

Affiliation QIMR Berghofer Medical Research Institute, Radiation Biology and Oncology Laboratory, Brisbane, Queensland, Australia

Thidathip Wongsurawat

Affiliations Department of Genome and Gene Expression Data Analysis, Bioinformatics Institute, Singapore, Singapore, School of Computer Engineering, Nanyang Technological University, Singapore, Singapore

Piroon Jenjaroenpoon

Affiliation Department of Genome and Gene Expression Data Analysis, Bioinformatics Institute, Singapore, Singapore

Vladimir A. Kuznetsov

Affiliations Department of Genome and Gene Expression Data Analysis, Bioinformatics Institute, Singapore, Singapore, School of Computer Engineering, Nanyang Technological University, Singapore, Singapore

Peter J. McKinnon

Affiliation Department of Genetics and Tumour Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Martin F. Lavin

martin.lavin@qimrberghofer.edu.au

Affiliations QIMR Berghofer Medical Research Institute, Radiation Biology and Oncology Laboratory, Brisbane, Queensland, Australia, School of Medicine, University of Queensland, Herston, Queensland, Australia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AJY OJB MFL. Performed the experiments: AJY OJB JEL PJM TW PJ VK JKC. Analyzed the data: AJY OJB MFL. Wrote the paper: AJY OJB TW VAK MFL. In charge of the mouse-breeding program: JEL. Provided the Tdp1 and Aptx mouse strains: PJM. Performed in silico RLFS prediction: TW PJ VK. Produced senataxin antibody: JKC.