About the Authors

Henrik Knecht

Contributed equally to this work with: Henrik Knecht, Sven C. Neulinger

Affiliation Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany

Sven C. Neulinger

Contributed equally to this work with: Henrik Knecht, Sven C. Neulinger

Affiliation Institute for General Microbiology (IFAM), Christian-Albrechts-University (CAU), Kiel, Germany

Femke Anouska Heinsen

Affiliation Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany

Carolin Knecht

Affiliation Institute of Medical Informatics and Statistics (IMIS), Christian-Albrechts-University (CAU), Kiel, Germany

Anke Schilhabel

Affiliation Institute for General Microbiology (IFAM), Christian-Albrechts-University (CAU), Kiel, Germany

Ruth A. Schmitz

Affiliation Institute for General Microbiology (IFAM), Christian-Albrechts-University (CAU), Kiel, Germany

Alexandra Zimmermann

Affiliation Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany

Vitor Martins dos Santos

Affiliations Systems and Synthetic Biology, Wageningen University, Wageningen, The Netherlands, LifeGlimmer GmbH, Berlin, Germany

Manuel Ferrer

Affiliation Laboratory of Enzyme Discovery, CSIC - Institute of Catalysis, Madrid, Spain

Philip C. Rosenstiel

Affiliation Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany

Stefan Schreiber

Affiliations Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany, Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany

Anette K. Friedrichs

These authors share senior authorship.

Affiliations Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany, Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany

Stephan J. Ott

s.ott@mucosa.de

These authors share senior authorship.

Affiliations Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University (CAU), Kiel, Germany, Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany

Competing Interests

LifeGlimmer GmbH is Start-up Company founded in 2012 by Prof. V. A. Pires Martins dos Santos, who is one of the co-authors of the manuscript. Prof. V. A. Pires Martins dos Santos primarily works at the University of Wageningen, The Netherlands. The shareholder status of the company has not compromised the objectivity or validity of the research, analyses, or interpretations in the paper. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VMdS SO. Performed the experiments: HK FAH AS AZ MF. Analyzed the data: HK SCN CK RAS VMdS MF AKF SO. Contributed reagents/materials/analysis tools: SCN CK VMdS MF. Wrote the paper: HK FAH RAS VMdS MF PCR SS AKF SO. Wrote application and received funding: SO.