About the Authors

Pere Domingo

Contributed equally to this work with: Pere Domingo, María del Mar Gutierrez

pdomingo@santpau.cat

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

María del Mar Gutierrez

Contributed equally to this work with: Pere Domingo, María del Mar Gutierrez

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

José Miguel Gallego-Escuredo

Affiliations Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain

Ferran Torres

Affiliation Biostatistics and Data Management Platform, Institut d′Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, Biostatistics Unit, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain

Gracia María Mateo

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

Joan Villarroya

Affiliations Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Institut de Recerca del Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain

Ignacio de los Santos

Affiliation Infectious Diseases Unit, Hospital de la Princesa, Madrid, Spain

Joan Carles Domingo

Affiliations Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain

Francesc Villarroya

Affiliations Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain

Luis Del Rio

Affiliation CETIR, Barcelona, Spain

Vicente Estrada

Affiliation Infectious Diseases Unit, Hospital Clínico de San Carlos, Madrid, Spain

Marta Giralt

Affiliations Department of Biochemistry and Molecular Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Institute of Biomedicine, University of Barcelona, Barcelona, Spain, Fisiopatología de la Obesidad y Nutrición, Centros de Investigación Biomédica en Red (CIBER), Santiago de Compostela, Spain

Competing Interests

This study was partly funded by an unrestricted grant from Merck, Sharp & Dohme, Spain, the producer of raltegravir. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PD MdMG FV VE MG. Performed the experiments: PD MdMG FV VE MG. Analyzed the data: PD MdMG FV VE MG. Contributed reagents/materials/analysis tools: JMG-E FT GMM JV IdelS JCD LdR. Wrote the paper: PD MdMG FV VE MG.