About the Authors

Stefan Handtke

Contributed equally to this work with: Stefan Handtke, Rebecca Schroeter

Affiliation Institute for Microbiology, University of Greifswald, Greifswald, Germany

Rebecca Schroeter

Contributed equally to this work with: Stefan Handtke, Rebecca Schroeter

Affiliation Pharmaceutical Biotechnology, Institute of Pharmacy, University of Greifswald, Greifswald, Germany

Britta Jürgen

Affiliation Pharmaceutical Biotechnology, Institute of Pharmacy, University of Greifswald, Greifswald, Germany

Karen Methling

Affiliation Institute of Biochemistry, University of Greifswald, Greifswald, Germany

Rabea Schlüter

Affiliation Institute for Microbiology, University of Greifswald, Greifswald, Germany

Dirk Albrecht

Affiliation Institute for Microbiology, University of Greifswald, Greifswald, Germany

Sacha A. F. T. van Hijum

Affiliation Centre for Molecular and Biomolecular Informatics (CMBI), Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; and Division Processing and Safety, NIZO Food Research B.V., Ede, The Netherlands

Johannes Bongaerts

Affiliation Department of Chemistry and Biotechnology, Aachen University of Applied Sciences, Jülich, Germany

Karl-Heinz Maurer

Affiliation AB Enzymes GmbH, Darmstadt, Germany

Michael Lalk

Affiliation Institute of Biochemistry, University of Greifswald, Greifswald, Germany

Thomas Schweder

Affiliations Pharmaceutical Biotechnology, Institute of Pharmacy, University of Greifswald, Greifswald, Germany, Institute of Marine Biotechnology, Greifswald, Germany

Michael Hecker

Affiliations Institute for Microbiology, University of Greifswald, Greifswald, Germany, Institute of Marine Biotechnology, Greifswald, Germany

Birgit Voigt

birgit.voigt@uni-greifswald.de

Affiliations Institute for Microbiology, University of Greifswald, Greifswald, Germany, Institute of Marine Biotechnology, Greifswald, Germany

Competing Interests

The transcriptome analysis for this study was financially supported by Henkel KGaA. Dr. Sacha A.F.T. van Hijum is affiliated to NIZO Food Research B.V., and Dr. Karl-Heinz Maurer to AB Enzymes GmbH. Dr. Karl-Heinz Maurer was formerly employed at the company Henkel AG & Co. KGaA (Düsseldorf, Germany) which was involved as an associated partner in one of the projects. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: SH R. Schroeter R. Schlüter JB KHM ML TS MH BV. Performed the experiments: SH R. Schroeter KM R. Schlüter DA. Analyzed the data: SH R. Schroeter BJ SvH KM. Wrote the paper: SH R. Schroeter KM R. Schlüter BV TS MH.