About the Authors
- Marco Fazzari
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Contributed equally to this work with: Marco Fazzari, Andrés Trostchansky
Affiliations Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Fondazione Ri.MED, Palermo, Italy
- Andrés Trostchansky
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Contributed equally to this work with: Marco Fazzari, Andrés Trostchansky
Affiliation Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay
- Francisco J. Schopfer
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Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Sonia R. Salvatore
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Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Beatriz Sánchez-Calvo
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Affiliation Departamento de Biología Experimental, Universidad de Jaén, Jaén, Andalucía, Spain
- Dario Vitturi
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Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Raquel Valderrama
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Affiliation Departamento de Biología Experimental, Universidad de Jaén, Jaén, Andalucía, Spain
- Juan B. Barroso
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Affiliation Departamento de Biología Experimental, Universidad de Jaén, Jaén, Andalucía, Spain
- Rafael Radi
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Affiliation Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay
- Bruce A. Freeman
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* E-mail: hrubbo@fmed.edu.uy (HR); freerad@pitt.edu (BAF)
Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
- Homero Rubbo
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* E-mail: hrubbo@fmed.edu.uy (HR); freerad@pitt.edu (BAF)
Affiliation Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay
Competing Interests
The authors have read the journal's policy and have the following conflicts: BAF and FJS acknowledge financial interest in Complexa, Inc. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AT MF FJS SRS RR BAF HR. Performed the experiments: AT MF FJS BSC DV. Analyzed the data: AT MF FJS SRS JBB RR BAF HR. Contributed reagents/materials/analysis tools: AT RV JBB RR BAF HR. Wrote the paper: AT MF FJS SRS JBB RR BAF HR.