About the Authors

Liang Xie

Contributed equally to this work with: Liang Xie, Qinming Zhou, Shigang Liu

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Institute of Neuroscience, Chongqing Medical University, Chongqing, China

Qinming Zhou

Contributed equally to this work with: Liang Xie, Qinming Zhou, Shigang Liu

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Institute of Neuroscience, Chongqing Medical University, Chongqing, China

Shigang Liu

Contributed equally to this work with: Liang Xie, Qinming Zhou, Shigang Liu

Affiliation Suzhou Xishan Zhongke Laboratory Animal Co., Ltd., Suzhou, China

Qingyuan Wu

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Institute of Neuroscience, Chongqing Medical University, Chongqing, China

Yongjia Ji

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Institute of Neuroscience, Chongqing Medical University, Chongqing, China

Lujun Zhang

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Fan Xu

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Wei Gong

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Narayan D. Melgiri

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Peng Xie

xiepeng@cqmu.edu.cn

Affiliations Department of Neurology, The First Affiliated Hospital at Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Institute of Neuroscience, Chongqing Medical University, Chongqing, China

Competing Interests

The Suzhou Xishan Zhongke Laboratory Animal Company, Ltd. (hereinafter “the Suzhou Company”) is a private (non-governmental) independent Chinese limited liability corporate entity with three operating subsidiaries: the Production Center for Laboratory Animals, the National Resource Center for Nonhuman Primates, and the Suzhou Drug Safety Evaluation & Research Center (see http://www.szxszk.com/jigou.do). One co-author, Shigang Liu, is currently employed by the Suzhou Company through its Production Center for Laboratory Animals subsidiary, but has no consulting relationship with nor any ownership interest in the Suzhou Company or its subsidiaries. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. All other co-authors have no employment, consulting, or ownership interests in the Suzhou Company or its subsidiaries. All co-authors do not share intellectual property/patent rights, nor any joint interests in products in development or marketed products with the Suzhou Company or its subsidiaries. All co-authors declare no other competing interests related to this study.

Author Contributions

Conceived and designed the experiments: LX PX. Performed the experiments: LX QZ SL QW YJ LZ. Analyzed the data: LX FX. Contributed reagents/materials/analysis tools: LX SL WG. Wrote the paper: LX NDM PX.