About the Authors

Saud N. Al Sifri

saudnafa@hotmail.com

Affiliation Endocrinology Department, Al Hada Military Hospitals, Taif, Saudi Arabia

Wael Almahmeed

Affiliation Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates

Sami Azar

Affiliation American University of Beirut Medical Center, Beirut, Lebanon

Osama Okkeh

Affiliation Istishari Hospital, Amman, Jordan

Peter Bramlage

Affiliation Institut für Pharmakologie und präventive Medizin, Mahlow, Germany

Claus Jünger

Affiliations Institut für Herzinfarktforschung, Ludwigshafen, Germany, University Medical Center, Johannes Gutenberg University, Mainz, Germany

Islam Halawa

Affiliation Medical Department, MSD Saudi Arabia, Riyadh, Saudi Arabia

Baishali Ambegaonkar

Affiliation Merck & Co., Inc., Whitehouse Station, New Jersey, United States of America

Sameh Wajih

Affiliation Medical Department, MSD United Arab Emirates, Abu Dhabi, United Arab Emirates

Philippe Brudi

Affiliation Merck & Co., Inc., Whitehouse Station, New Jersey, United States of America

Competing Interests

Saud Al Sifri (SAS), Wael Almahmeed (WAM), Sami T. Azar (STA), and Osama Okkeh (OO) are board members and consultants, Peter Bramlage (PBra) and Claus Jünger (CJ) are consultants for Merck & Co Ltd. Baishali Ambegaonkar (BA), Philippe Brudi (PBru), and Sameh Wajih (SW) are employees of Merck & Co Ltd., whose company funded this study. Islam Halawa (IH) has been an employee of Merck & Co Ltd. at the time of the conduct of the study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Analyzed the data: CJ P. Bramlage. Contributed to study concept and design: BA P. Brudi IH CJ SW. Contributed to data acquisition and interpretation of the study: SAS WA SA OO. Drafted the manuscript: P. Bramlage. Revised the article for important intellectual content: SAS WA SA OO P. Bramlage CJ IH BA SW P. Brudi. Read and approved the final manuscript to be published: SAS WA SA OO P. Bramlage CJ IH BA SW P. Brudi.