About the Authors

Anne Seidlitz

anne.seidlitz@uni-greifswald.de

Affiliation Institute of Pharmacy, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany

Nadine Kotzan

Affiliation Institute of Pharmacy, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany

Stefan Nagel

Affiliation Institute of Pharmacy, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany

Thomas Reske

Affiliation Institute for Biomedical Engineering, University of Rostock, Rostock, Germany

Niels Grabow

Affiliation Institute for Biomedical Engineering, University of Rostock, Rostock, Germany

Claus Harder

Affiliation Biotronik SE & Co. KG, Erlangen, Germany

Svea Petersen

Affiliation Institute for Biomedical Engineering, University of Rostock, Rostock, Germany

Katrin Sternberg

Affiliation Institute for Biomedical Engineering, University of Rostock, Rostock, Germany

Werner Weitschies

Affiliation Institute of Pharmacy, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany

Competing Interests

CH is an employee of Biotronik SE & Co., whose company provided the uncoated Pantera Lux balloon catheters used in this study. B. Braun Melsungen AG provided the hemostatic valves used in this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AS SN WW. Performed the experiments: AS NK TR SP. Analyzed the data: AS NK SN WW. Contributed reagents/materials/analysis tools: AS SN TR NG CH SP KS WW. Wrote the paper: AS SN WW.