About the Authors

Ying Zhang

Contributed equally to this work with: Ying Zhang, Erxia Yang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Erxia Yang

Contributed equally to this work with: Ying Zhang, Erxia Yang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Jing Pu

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Longding Liu

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Yanchun Che

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Jingjing Wang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Yun Liao

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Lichun Wang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Dong Ding

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Ting Zhao

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Na Ma

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Ming Song

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Xi Wang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Dong Shen

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Donghong Tang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Hongtai Huang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Zhixiao Zhang

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Dai Chen

Affiliation Department of Bioinformatic analyses, Novel Bioinformatics Co., Ltd, Shanghai, China

Mingfei Feng

Affiliation Department of Bioinformatic analyses, Novel Bioinformatics Co., Ltd, Shanghai, China

Qihan Li

liqihan@imbcams.com.cn

Affiliation Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Science and Peking Union Medical College, Kunming, China

Competing Interests

The Institute of Medical Biology paid Novel Bioinformatics Co. for the Genechip microarray assay. All the research interests (including research results, patents, products, employment, consultancy, etc.) belong to the Institute of Medical Biology, according to the contract between Institute of Medical Biology and Novel Bioinformatics Co. Both Dai Chen and Mingfei Feng from Novel Bioinformatics Co., who are the analysts, assume this microarray analytical work. They kindly re-analyzed the results of microarray assay according to the reviewers during major revision, so all authors agree to put their name into the authors list. The authors (including the Institute of Medical Biology and Novel Bioinformatics Co.) have declared that no competing interests exist and this does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: QL YZ EY. Performed the experiments: QL YZ EY JP LL JW YL DD TZ NM XW DS HH ZZ. Analyzed the data: QL YZ EY DC MF. Contributed reagents/materials/analysis tools: LW MS DT. Wrote the paper: QL YZ EY YC. Logistical support in the field: QL YC.