About the Authors

Szu-Ming Chen

Affiliations Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan, Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan

Chi-Chen Fan

Affiliations Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan, Department of Physiology, Mackay Memorial Hospital, Taipei, Taiwan

Ming-Shiuan Chiue

Affiliations Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering and Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, Graduate Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan

Chi Chou

Affiliation Department of Physiology, Mackay Memorial Hospital, Taipei, Taiwan

Jyh-Horng Chen

jyhhchen2@gmail.com (JHC); rshseu@ntu.edu.tw (RSH)

Affiliation Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering and Molecular Imaging Center, National Taiwan University, Taipei, Taiwan

Ruey-Shyang Hseu

jyhhchen2@gmail.com (JHC); rshseu@ntu.edu.tw (RSH)

Affiliation Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan

Competing Interests

This study was funded by Taiwan Sigma Biotech Corp. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: SMC RSH. Performed the experiments: SMC CCF MSC CC. Analyzed the data: SMC CCF MSC RSH. Contributed reagents/materials/analysis tools: SMC JHC RSH. Wrote the paper: SMC.