About the Authors

Fidele Ntie-Kang

ntiekfidele@gmail.com

Affiliations Chemical and Bioactivity Information Centre, Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon, Center Atomic Molecular Physics, Optics and Quantum, Faculty of Science, University of Douala, Douala, Cameroon, Department of Pharmaceutical Sciences, Martin-Luther University of Halle-Wittenberg, Halle (Saale), Germany

Denis Zofou

Affiliation Biotechnology Unit, Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, Buea, Cameroon

Smith B. Babiaka

Affiliation Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon

Rolande Meudom

Affiliation Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon

Michael Scharfe

Affiliation Department of Pharmaceutical Sciences, Martin-Luther University of Halle-Wittenberg, Halle (Saale), Germany

Lydia L. Lifongo

Affiliation Chemical and Bioactivity Information Centre, Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon

James A. Mbah

Affiliation Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon

Luc Meva’a Mbaze

Affiliation Department of Chemistry, Faculty of Science, University of Douala, Douala, Cameroon

Wolfgang Sippl

Affiliation Department of Pharmaceutical Sciences, Martin-Luther University of Halle-Wittenberg, Halle (Saale), Germany

Simon M. N. Efange

Affiliation Department of Chemistry, Faculty of Science, University of Buea, Buea, Cameroon

Competing Interests

The academic license for this work was generously offered by Schrodinger Inc. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: WS LMM DZ FNK SMNE. Performed the experiments: FNK DZ MS SBB. Analyzed the data: MS FNK DZ SBB RM JAM. Contributed reagents/materials/analysis tools: WS DZ FNK LMM MS RM SMNE JAM LLL. Wrote the paper: FNK DZ SBB MS.