Ashwagandha (Withania somnifera) Reverses β-Amyloid1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND)

Kesava Rao Venkata Kurapati; Venkata Subba Rao Atluri; Thangavel Samikkannu; Madhavan P. N. Nair

doi:10.1371/journal.pone.0077624

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Peer-reviewed

Research Article

Ashwagandha (Withania somnifera) Reverses β-Amyloid_1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND)

Kesava Rao Venkata Kurapati,

Affiliation Department of Immunology, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A. Maidique Campus, Miami, Florida, United States of America
⨯
Venkata Subba Rao Atluri,

Affiliation Department of Immunology, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A. Maidique Campus, Miami, Florida, United States of America
⨯
Thangavel Samikkannu,

Affiliation Department of Immunology, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A. Maidique Campus, Miami, Florida, United States of America
⨯
Madhavan P. N. Nair

* E-mail: nairm@fiu.edu

Affiliation Department of Immunology, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A. Maidique Campus, Miami, Florida, United States of America
⨯

Ashwagandha (Withania somnifera) Reverses β-Amyloid_1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND)

Kesava Rao Venkata Kurapati,
Venkata Subba Rao Atluri,
Thangavel Samikkannu,
Madhavan P. N. Nair

Published: October 16, 2013
https://doi.org/10.1371/journal.pone.0077624

About the Authors

Kesava Rao Venkata Kurapati

Affiliation Department of Immunology, Institute of NeuroImmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A. Maidique Campus, Miami, Florida, United States of America

Venkata Subba Rao Atluri

Thangavel Samikkannu

Madhavan P. N. Nair

* E-mail: nairm@fiu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KRVK MPNN. Performed the experiments: KRVK VSRA TS. Analyzed the data: KRVK VSRA TS MPNN. Contributed reagents/materials/analysis tools: MPNN. Wrote the manuscript: KRVK MPNN.

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Alzheimer's disease
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Memory
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