About the Authors

Nigel Klein

n.klein@ucl.ac.uk

Affiliation Institute of Child Health, University College London, London, United Kingdom

Delali Sefe

Affiliation Institute of Child Health, University College London, London, United Kingdom

Ilaria Mosconi

Affiliation AIDS Reference Center, University of Padova, Padova, Italy

Marisa Zanchetta

Affiliation AIDS Reference Center, University of Padova, Padova, Italy

Hannah Castro

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Marianne Jacobsen

Affiliation Institute of Child Health, University College London, London, United Kingdom

Hannah Jones

Affiliation Institute of Child Health, University College London, London, United Kingdom

Stefania Bernardi

Affiliation Ospedale del Bambino Gesù, Rome, Italy

Deenan Pillay

Affiliation University College London/Medical Research Council Centre for Medical Molecular Virology, University College London Medical School, London, United Kingdom

Carlo Giaquinto

Affiliation Department of Paediatrics, University of Padova, Padova, Italy

A. Sarah Walker

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Diana M. Gibb

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Anita De Rossi

Affiliation AIDS Reference Center, University of Padova, Padova, Italy

on Behalf of the Paediatric European Network for Treatment of AIDS (PENTA) 11 Trial Team

Membership of the Paediatric European Network for Treatment of AIDS (PENTA) 11 Trial Team is provided in the Acknowledgments.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NK HC DP CG ASW DMG ADR. Laboratory work in Italy: ADR IM SB MZ. Laboratory work in UK: NK DS MJ HJ. Final statistical analysis: HC. Contributed to the interpretation of the data: NK DS IM MZ HC MJ HJ SB DP CG ASW DMG ADR. Wrote the first draft of the paper: NK ADR HC. Commented extensively, revised the report critically, and approved the final version: NK DS IM MZ HC MJ HJ SB DP CG ASW DMG ADR.