About the Authors

Xiao-Jian Han

Affiliations Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Japan Society for the Promotion of Science, Tokyo, Japan, Institute of Translational Medicine, Nanchang University, Nanchang, China

Ling-Fei Sun

Affiliation Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Yuki Nishiyama

Affiliation Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Bin Feng

Affiliations Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Department of Biotechnology, Dalian medical University, Dalian, China

Hiroyuki Michiue

Affiliation Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Masaharu Seno

Affiliation Department of Medical and Bioengineering Science, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Hideki Matsui

Affiliation Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Kazuhito Tomizawa

tomikt@kumamoto-u.ac.jp

Affiliation Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XH KT. Performed the experiments: XH LS YN. Analyzed the data: XH BF. Contributed reagents/materials/analysis tools: H. Michiue MS H. Matsui. Wrote the manuscript: XH KT.