About the Authors

Bart J. G. Broeckx

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Frank Coopman

Affiliation Holbigenetics NV, Waarschoot, Belgium

Geert E. C. Verhoeven

Affiliation Department of Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Wim Van Haeringen

Affiliation Dr. Van Haeringen Laboratorium b.v., Wageningen, The Netherlands

Leanne van de Goor

Affiliation Dr. Van Haeringen Laboratorium b.v., Wageningen, The Netherlands

Tim Bosmans

Affiliation Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Ingrid Gielen

Affiliation Department of Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Jimmy H. Saunders

Affiliation Department of Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Sandra S. A. Soetaert

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Henri Van Bree

Affiliation Department of Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Christophe Van Neste

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Filip Van Nieuwerburgh

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Bernadette Van Ryssen

Affiliation Department of Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Elien Verelst

Affiliation Faculty of Applied Bio-engineering, University College Ghent, Melle, Belgium

Katleen Van Steendam

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Dieter Deforce

Dieter.Deforce@Ugent.be

Affiliation Laboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium

Competing Interests

The authors have the following interests: The authors received funding from Royal Canin to print publicity material (posters) for our research project. Co-author Frank Coopman is employed by Holbigenetics NV. Co-authors Wim Van Haeringen and Leanne van de Goor are employed by Dr. Van Haeringen Laboratorium b.v. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BJGB FC GECV WVH LVDG DD. Performed the experiments: BJGB WVH LVDG TB IG JHS SSAS HVB CVN FVN BVR EV KVS. Analyzed the data: BJGB FC GECV WVH LVDG EV DD. Contributed reagents/materials/analysis tools: BJGB FC GECV WVH LVDG TB IG JHS SSAS HVB CVN FVN BVR EV KVS DD. Wrote the paper: BJGB FC GECV WVH LVDG TB IG JHS SSAS HVB CVN FVN BVR EV KVS DD.