About the Authors

Magda Møller

Affiliation Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark

Søren S. Nielsen

Affiliations Department of Structural Biophysics, University of Copenhagen, Copenhagen, Denmark, Cornell High Energy Synchrotron Source (CHESS) and Macromolecular Diffraction Facility at CHESS (MacCHESS), Cornell University, Ithaca, New York, United States of America

Sekar Ramachandran

Affiliation Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America

Yuxing Li

Affiliation Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America

Giancarlo Tria

Affiliations European Molecular Biology Laboratory, Hamburg Outstation c/o DESY, Hamburg, Germany, Center for Bioinformatics, University of Hamburg, Hamburg, Germany

Werner Streicher

Affiliation Protein Function and Interactions, Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark

Maxim V. Petoukhov

Affiliation European Molecular Biology Laboratory, Hamburg Outstation c/o DESY, Hamburg, Germany

Richard A. Cerione

Affiliations Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States of America, Department of Molecular Medicine, Cornell University, Ithaca, New York, United States of America

Richard E. Gillilan

Affiliation Cornell High Energy Synchrotron Source (CHESS) and Macromolecular Diffraction Facility at CHESS (MacCHESS), Cornell University, Ithaca, New York, United States of America

Bente Vestergaard

bente.vestergaard@sund.ku.dk

Affiliation Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MM SSN SR YL GT WS MVP RAC REG BV. Performed the experiments: MM SSN SR YL GT WS MVP RAC REG BV. Analyzed the data: MM SSN SR YL GT WS MVP RAC REG BV. Contributed reagents/materials/analysis tools: MM SSN SR YL GT WS MVP RAC REG BV. Wrote the paper: MM SSN SR YL GT WS MVP RAC REG BV.