About the Authors

James Rooney

Contributed equally to this work with: James Rooney, Susan Byrne

jrooney@rcsi.ie

Affiliation Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Dublin, Ireland

Susan Byrne

Contributed equally to this work with: James Rooney, Susan Byrne

Affiliation Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Dublin, Ireland

Mark Heverin

Affiliation Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Dublin, Ireland

Bernie Corr

Affiliation Department of Neurology, Beaumont Hospital, Dublin, Ireland

Marwa Elamin

Affiliation Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Dublin, Ireland

Anthony Staines

Affiliation School of Nursing and Human Sciences, Dublin City University, Dublin, Ireland

Ben Goldacre

Affiliation Department of Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Orla Hardiman

Affiliations Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Dublin, Ireland, Department of Neurology, Beaumont Hospital, Dublin, Ireland

Competing Interests

The authors have read the journal’s policy and have the following conflicts: Professor Orla Hardiman: Prof. Orla Hardiman has received speaking honoraria from Janssen Cilag, Biogen Idec, Sanofi Aventis and Merck-Serono. She has been a member of advisory panels for Biogen Idec, Allergen, Ono Pharmaceuticals, Novartis, Cytokinetics and Sanofi Aventis. She serves as Editor-in-Chief of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The remaining authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JR SB ME OH. Analyzed the data: JR SB. Wrote the paper: JR SB OH. Data collection: SB MH BC ME OH. Critical review, contributions to analysis strategy, manuscript edits and approval: AS BG OH.