About the Authors

Emőke-Ágnes Horvát

Affiliations Interdisciplinary Center for Scientific Computing, University of Heidelberg, Heidelberg, Germany, Network Analysis and Graph Theory, Technical University of Kaiserslautern, Kaiserslautern, Germany

Jitao David Zhang

Affiliation Computational Biology and Bioinformatics, Pharmaceutical Research and Early Development, Basel, Switzerland

Stefan Uhlmann

Current address: Department of Neurology, University Heidelberg, Heidelberg, Germany

Affiliation Division of Molecular Genome Analysis, German Cancer Research Institute, Heidelberg, Germany

Özgür Sahin

Affiliation Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Katharina Anna Zweig

zweig@cs.uni-kl.de

Affiliation Network Analysis and Graph Theory, Technical University of Kaiserslautern, Kaiserslautern, Germany

Competing Interests

The study was not funded by F. Hoffmann-La Roche, the employer of Jitao David Zhang, in any form. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: EAH KAZ JDZ. Performed the experiments: EAH JDZ. Analyzed the data: EAH JDZ SU OS KAZ. Contributed reagents/materials/analysis tools: EAH JDZ SU OS KAZ. Wrote the paper: EAH KAZ JDZ OS SU.