About the Authors

Christopher Lambers

Affiliation Division of Respiratory Medicine, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

Michael Roth

Affiliation Pulmonary Cell Research/Pneumologie, Department Biomedicine/Internal Medicine, University Basel/University Hospital, Basel, Basel, Switzerland

Jun Zhong

Affiliation Pulmonary Cell Research/Pneumologie, Department Biomedicine/Internal Medicine, University Basel/University Hospital, Basel, Basel, Switzerland

Christoph Campregher

Affiliation Christian Doppler Laboratory for Molecular Cancer Chemoprevention, Division of Gastroenterology and Hepatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria

Petra Binder

Affiliation Division of Respiratory Medicine, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

Bernhard Burian

Affiliation Division of Respiratory Medicine, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

Ventzislav Petkov

Affiliation Division of Respiratory Medicine, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

Lutz-Henning Block

lutz-henning.block@meduniwien.ac.at

Affiliation Division of Respiratory Medicine, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

Competing Interests

The authors have the following interests. This study was partly supported by an unrestricted grant from Actelion Pharmaceuticals. C.L. has received a travel grant from Actelion Pharmaceuticals. The Bosentan used in this study is an Actelion Pharmaceuticals product. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: CL MR VP LHB. Performed the experiments: CL MR JZ PB. Analyzed the data: CL MR VP LHB. Contributed reagents/materials/analysis tools: CC BB VP. Wrote the manuscript: CL MR LHB.