About the Authors

Kensuke Tomio

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Kei Kawana

Contributed equally to this work with: Kei Kawana, Makoto Arita

kkawana-tky@umin.org (KK); marita@mol.f.u-tokyo.ac.jp (MA)

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Ayumi Taguchi

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Yosuke Isobe

Affiliation Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Ryo Iwamoto

Affiliation Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Aki Yamashita

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Satoko Kojima

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Mayuyo Mori

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Takeshi Nagamatsu

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Takahide Arimoto

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Katsutoshi Oda

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Yutaka Osuga

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Yuji Taketani

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Jing X. Kang

Affiliation Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Hiroyuki Arai

Affiliation Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Makoto Arita

Contributed equally to this work with: Kei Kawana, Makoto Arita

kkawana-tky@umin.org (KK); marita@mol.f.u-tokyo.ac.jp (MA)

Affiliation Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

Shiro Kozuma

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Tomoyuki Fujii

Affiliation Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KT KK HA MA YO YT S. Kozuma TF. Performed the experiments: KT KK YI RI HA MA. Analyzed the data: KT KK YI RI HA MA. Contributed reagents/materials/analysis tools: KT KK AT AY S. Kojima MM TN TA KO JXK. Wrote the paper: KT KK YO MA.