About the Authors

Daniah Trabzuni

Contributed equally to this work with: Daniah Trabzuni, Mina Ryten

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Mina Ryten

Contributed equally to this work with: Daniah Trabzuni, Mina Ryten

Affiliation Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom

Warren Emmett

Affiliation University College London Genetics Institute, University College London, London, United Kingdom

Adaikalavan Ramasamy

Affiliation Department of Medical and Molecular Genetics, King's College London, Guy's Hospital, London, United Kingdom

Karl J. Lackner

Affiliation Institute of Clinical Chemistry and Laboratory Medicine, University Medical Centre Mainz, Mainz, Germany

Tanja Zeller

Affiliation University Heart Center Hamburg, Clinic for General and Interventional Cardiology, Hamburg, Germany

Robert Walker

Affiliation MRC Sudden Death Brain Bank Project, University of Edinburgh, Department of Neuropathology, Edinburgh, Scotland, United Kingdom

Colin Smith

Affiliation MRC Sudden Death Brain Bank Project, University of Edinburgh, Department of Neuropathology, Edinburgh, Scotland, United Kingdom

Patrick A. Lewis

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, School of Pharmacy, University of Reading, Whiteknights, Reading, United Kingdom

Adamantios Mamais

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Reta Lila Weston Institute of Neurological Studies, London, United Kingdom

Rohan de Silva

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Reta Lila Weston Institute of Neurological Studies, London, United Kingdom

Jana Vandrovcova

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Reta Lila Weston Institute of Neurological Studies, London, United Kingdom

International Parkinson Disease Genomics Consortium (IPDGC)

A full list of IPDGC consortium members is provided in Table S1.

Dena Hernandez

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Michael A. Nalls

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Manu Sharma

Affiliation Division of Neurodegenerative Disorders, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany

Sophie Garnier

Affiliation Pierre and Marie Curie University, Institut National de la Santé et de la Recherche Médicale UMRS 937, Paris, France

Suzanne Lesage

Affiliation CRICM, University Pierre et Marie Curie, Institut National de la Santé et de la Recherche Médicale UMRS 975, CNRS UMR 7225, Hospital Pitié-Salpêtrière, Paris, France

Javier Simon-Sanchez

Affiliation Department of Clinical Genetics, Section of Medical Genomics, VU University Medical Centre, Amsterdam, The Netherlands

Thomas Gasser

Affiliation Division of Neurodegenerative Disorders, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany

Peter Heutink

Affiliation Department of Clinical Genetics, Section of Medical Genomics, VU University Medical Centre, Amsterdam, The Netherlands

Alexis Brice

Affiliation CRICM, University Pierre et Marie Curie, Institut National de la Santé et de la Recherche Médicale UMRS 975, CNRS UMR 7225, Hospital Pitié-Salpêtrière, Paris, France

Andrew Singleton

Affiliation Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Huaibin Cai

Affiliation Unit of Transgenesis, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Eric Schadt

Affiliation Institute for Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America

Nicholas W. Wood

Affiliation Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom

Rina Bandopadhyay

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Reta Lila Weston Institute of Neurological Studies, London, United Kingdom

Michael E. Weale

Affiliation Department of Medical and Molecular Genetics, King's College London, Guy's Hospital, London, United Kingdom

John Hardy

Affiliations Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, United Kingdom, Reta Lila Weston Institute of Neurological Studies, London, United Kingdom

Vincent Plagnol

v.plagnol@ucl.ac.uk

Affiliation University College London Genetics Institute, University College London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DT MR AR CS PL RD MW JH VP. Performed the experiments: DT MR AR RW PL AM JV RB MS DH SL JS. Analyzed the data: DT MR AR PL RB MW JH VP SG TZ AR WE MN. Contributed reagents/materials/analysis tools: RW CS PL AM RD JV HC ES NW RB MW JH AS PH TG KL AB. Wrote the paper: DT MR PL RB VP.