About the Authors

Zhinan Jin

zjin@aliosbiopharma.com (ZJ); jdeval@aliosbiopharma.com (JD)

Affiliation Alios BioPharma, Inc., South San Francisco, California, United States of America

Lucas K. Smith

Affiliation Alios BioPharma, Inc., South San Francisco, California, United States of America

Vivek K. Rajwanshi

Affiliation Alios BioPharma, Inc., South San Francisco, California, United States of America

Baek Kim

Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

Jerome Deval

zjin@aliosbiopharma.com (ZJ); jdeval@aliosbiopharma.com (JD)

Affiliation Alios BioPharma, Inc., South San Francisco, California, United States of America

Competing Interests

ZJ, LKS, VKR and JD are current or former employees of Alios BioPharma, Inc. BK is collaborating with Alios BioPharma, Inc. Alios BioPharma funded this study. T-705 is developed by Toyama Chemical Co., LTD. Co-author BK is a PLOS ONE Editorial Board member. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ZJ JD. Performed the experiments: ZJ LKS JD. Analyzed the data: ZJ JD. Contributed reagents/materials/analysis tools: VKR BK. Wrote the paper: ZJ JD.