About the Authors

Chun-Mao Lin

Affiliations Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Orthopedics Research Center, Taipei Medical University Hospital, Taipei, Taiwan

Chia-Lang Fang

Affiliations Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan

You-Cheng Hseu

Affiliations Department of Cosmeceutics, China Medical University, Taichung, Taiwan, Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Chun-Liang Chen

Affiliation Department of Surgery, Chi Mei Hospital Chiali, Tainan, Taiwan

Jin-Wun Wang

Affiliation Department of Surgery, Chi Mei Hospital Chiali, Tainan, Taiwan

Sheng-Lung Hsu

Affiliation Department of Surgery, Chi Mei Hospital Chiali, Tainan, Taiwan

Ming-Dao Tu

Affiliation Department of Family Medicine, Chi Mei Hospital Chiali, Tainan, Taiwan

Shih-Ting Hung

Affiliation Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan

Chein Tai

Affiliation Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan

Yih-Huei Uen

Contributed equally to this work with: Yih-Huei Uen, Kai-Yuan Lin

Affiliations Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan, Superintendent’s Office, Chi Mei Hospital Chiali, Tainan, Taiwan, Institute of Biomedical Engineering, Southern Taiwan University of Science and Technology, Tainan, Taiwan

Kai-Yuan Lin

Contributed equally to this work with: Yih-Huei Uen, Kai-Yuan Lin

d84306@yahoo.com.tw

Affiliations Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan, Department of Biotechnology, Chia Nan University of Pharmacy and Science, Tainan, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CML YHU KYL. Performed the experiments: CLF YCH STH. Analyzed the data: CLF YCH MDT CT KYL. Contributed reagents/materials/analysis tools: CLC JWW SLH. Wrote the paper: CML YHU KYL.