About the Authors
- Patrick C. Hermann
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Affiliation Stem Cells and Cancer Group, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Sara M. Trabulo
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Affiliation Stem Cells and Cancer Group, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Bruno Sainz Jr
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Affiliation Stem Cells and Cancer Group, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Anamaria Balic
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Affiliation Stem Cells and Cancer Group, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Elena Garcia
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Affiliation Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Stephan A. Hahn
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Affiliation Department of Molecular GI-Oncology, Ruhr-University Bochum, Bochum, Germany
- Mallaredy Vandana
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Affiliation Nanomedicine Laboratory, Institute of Life Sciences, Bhubaneswar, India
- Sanjeeb K. Sahoo
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Affiliation Nanomedicine Laboratory, Institute of Life Sciences, Bhubaneswar, India
- Patrizia Tunici
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Affiliation Department of Oncology, Siena Biotech S.p.A., Siena, Italy
- Annette Bakker
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Affiliation Children’s Tumor Foundation, New York, New York, United States of America
- Manuel Hidalgo
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Affiliation Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
- Christopher Heeschen
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* E-mail: cheeschen@cnio.es
Affiliation Stem Cells and Cancer Group, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
Competing Interests
Two of the authors are currently (Patrizia Tunici) or were until recently (Annette Bakker) employed by the commercial funder of this research 'Siena Biotech S.p.A'. Patrizia Tunici and Annette Bakker developed and validated SIBI-C1, but were not involved in the design and data analysis of the present study. The authors also confirm that this does not alter their adherence to all the PLOS ONE policies on sharing data and materials. No other relevant declarations are made relating to employment, consultancy, patents, products in development or marketed products, etc.
Author Contributions
Conceived and designed the experiments: PCH SMT SKS CH. Performed the experiments: PCH SMT BS A. Balic. Analyzed the data: PCH SMT PT A. Balic CH BS EG. Contributed reagents/materials/analysis tools: SAH MH PT A. Bakker MV SKS. Wrote the paper: PCH BS CH.