About the Authors

Timothy D. O’Connor

timothydoconnor@gmail.com (TDO); akeyj@u.washington.edu (JMA)

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Adam Kiezun

Affiliations Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Michael Bamshad

Affiliations Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America, Department of Pediatrics, University of Washington, Seattle, Washington, United States of America

Stephen S. Rich

Affiliation Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America

Joshua D. Smith

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Emily Turner

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

NHLBIGO Exome Sequencing Project

Membership of the NHLBI GO Exome Sequencing Project is provided in File S1.

ESP Population Genetics, Statistical Analysis Working Group

‡ Membership of the NHLBI GO Exome Sequencing Project is provided in File S1.

Suzanne M. Leal

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Joshua M. Akey

timothydoconnor@gmail.com (TDO); akeyj@u.washington.edu (JMA)

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TDO MJB SSR SML JMA. Performed the experiments: TDO. Analyzed the data: TDO JMA. Contributed reagents/materials/analysis tools: TDO AK MJB SSR JDS ET. Wrote the paper: TDO SML JMA.