About the Authors

Firdaus A. A. Mohamed Hoesein

fmohamedhoesein@gmail.com

Affiliations Department of Respiratory Medicine, Division of Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands

Pim A. de Jong

Affiliation Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands

Jan-Willem J. Lammers

Affiliation Department of Respiratory Medicine, Division of Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands

Willem PThM Mali

Affiliation Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands

Michael Schmidt

Affiliation Fraunhofer MEVIS, Institute for Medical Image Computing, Bremen, Germany

Harry J. de Koning

Affiliation Department of Public Health, Erasmus MC, Rotterdam, The Netherlands

Carlijn van der Aalst

Affiliation Department of Public Health, Erasmus MC, Rotterdam, The Netherlands

Matthijs Oudkerk

Affiliation Center for Medical Imaging – North East Netherlands, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

Rozemarijn Vliegenthart

Affiliation Department of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

Bram van Ginneken

Affiliation Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Eva M. van Rikxoort

Affiliation Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Pieter Zanen

Affiliation Department of Respiratory Medicine, Division of Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands

Competing Interests

HK is member of the medical advisory board of Roche Diagnostics. Siemens Germany and Roche Diagnostics provided funding towards this study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FMH PZ PJ. Performed the experiments: FMH PZ PJ. Analyzed the data: FMH PZ PJ. Wrote the paper: FMH PZ PJ BG ER MS JWL WM HK CA MO RV. Responsible for the quantification of structural lung changes on computed tomography: BG ER MS.