About the Authors

Rene Raphemot

Affiliations Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Matthew F. Rouhier

Affiliation Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America

Corey R. Hopkins

Affiliations Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Rocco D. Gogliotti

Affiliations Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Kimberly M. Lovell

Affiliations Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Rebecca M. Hine

Affiliation Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

Dhairyasheel Ghosalkar

Affiliation Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

Anthony Longo

Affiliation Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

Klaus W. Beyenbach

Affiliation Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America

Jerod S. Denton

jerod.s.denton@vanderbilt.edu (JSD); piermarini.1@osu.edu (PMP)

Affiliations Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Institute for Global Health, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Peter M. Piermarini

jerod.s.denton@vanderbilt.edu (JSD); piermarini.1@osu.edu (PMP)

Affiliation Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RR MFR CRH KWB JSD PMP. Performed the experiments: RR MFR RMH DG AL PMP. Analyzed the data: RR MFR CRH RMH KWB JSD PMP. Contributed reagents/materials/analysis tools: CRH RDG KML JSD. Wrote the paper: RR MFR KWB JSB PMP. Performed medicinal chemistry: CRH RDG KML.