Passing Messages between Biological Networks to Refine Predicted Interactions

Kimberly Glass; Curtis Huttenhower; John Quackenbush; Guo-Cheng Yuan

doi:10.1371/journal.pone.0064832

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Open Access

Peer-reviewed

Research Article

Passing Messages between Biological Networks to Refine Predicted Interactions

Kimberly Glass,

Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Curtis Huttenhower,

Affiliation Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
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John Quackenbush,

Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Guo-Cheng Yuan

* E-mail: gcyuan@jimmy.harvard.edu

Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯

Passing Messages between Biological Networks to Refine Predicted Interactions

Kimberly Glass,
Curtis Huttenhower,
John Quackenbush,
Guo-Cheng Yuan

Published: May 31, 2013
https://doi.org/10.1371/journal.pone.0064832

About the Authors

Kimberly Glass

Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Curtis Huttenhower

Affiliation Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

John Quackenbush

Guo-Cheng Yuan

* E-mail: gcyuan@jimmy.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KG CH JQ GY. Performed the experiments: KG. Analyzed the data: KG. Contributed reagents/materials/analysis tools: KG. Wrote the paper: KG CH JQ GY.

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Genetic networks
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Network motifs
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Protein interaction networks
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Gene regulation
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Gene regulatory networks
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Cellular stress responses
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Gene expression
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Network analysis
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