About the Authors

Geoffrey Férir

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Mariya I. Petrova

Affiliations Centre of Microbial and Plant Genetics, University of Leuven, Leuven, Belgium, Department of Bioscience Engineering, Antwerp University, Antwerp, Belgium

Graciela Andrei

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Dana Huskens

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Bart Hoorelbeke

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Robert Snoeck

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Jos Vanderleyden

Affiliation Centre of Microbial and Plant Genetics, University of Leuven, Leuven, Belgium

Jan Balzarini

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Stefan Bartoschek

Affiliation Sanofi R&D, Frankfurt am Main, Germany

Mark Brönstrup

Affiliation Sanofi R&D, Frankfurt am Main, Germany

Roderich D. Süssmuth

Affiliation Technische Universität Berlin, Fakultät II – Institut für Chemie; Berlin, Germany

Dominique Schols

dominique.schols@rega.kuleuven.be

Affiliation Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Competing Interests

This study was partly funded by Dormeur Services Inc. Co-authors Stefan Bartoschek and Mark Brönstrup are employed by Sanofi. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GF GA JV JB SB MB RDS DS. Performed the experiments: GF MIP GA DH BH. Analyzed the data: GF MIP GA DH BH RS JV DS. Contributed reagents/materials/analysis tools: SB MB RDS. Wrote the paper: GF MIP JV JB DH MB RDS DS.