Population Diversification in Staphylococcus aureus Biofilms May Promote Dissemination and Persistence

Victoria J. Savage; Ian Chopra; Alex J. O’Neill

doi:10.1371/journal.pone.0062513

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Open Access

Peer-reviewed

Research Article

Population Diversification in Staphylococcus aureus Biofilms May Promote Dissemination and Persistence

Victoria J. Savage,

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom
⨯
Ian Chopra,

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom
⨯
Alex J. O’Neill

* E-mail: a.j.oneill@leeds.ac.uk

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom
⨯

Population Diversification in Staphylococcus aureus Biofilms May Promote Dissemination and Persistence

Victoria J. Savage,
Ian Chopra,
Alex J. O’Neill

Published: April 30, 2013
https://doi.org/10.1371/journal.pone.0062513

About the Authors

Victoria J. Savage

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom

Ian Chopra

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom

Alex J. O’Neill

* E-mail: a.j.oneill@leeds.ac.uk

Affiliation Antimicrobial Research Centre, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VJS IC AJO. Performed the experiments: VJS. Analyzed the data: VJS. Contributed reagents/materials/analysis tools: VJS IC AJO. Wrote the paper: VJS IC AJO.

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Bacterial biofilms
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Staphylococcus aureus
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Proteolysis
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Biofilm culture
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Evolutionary emergence
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Phenotypes
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Proteases
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Staphylococcal infection
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