About the Authors

Yaoliang Chen

Affiliation School of Computer Science, Fudan University, Shanghai, China

Ji Hong

Affiliation School of Computer Science, Fudan University, Shanghai, China

Wanyun Cui

Affiliation School of Computer Science, Fudan University, Shanghai, China

Jacques Zaneveld

Affiliation Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Wei Wang

Affiliation School of Computer Science, Fudan University, Shanghai, China

Richard Gibbs

Affiliation Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Yanghua Xiao

shawyh@fudan.edu.cn (YX); ruichen@bcm.edu (RC)

Affiliation School of Computer Science, Fudan University, Shanghai, China

Rui Chen

shawyh@fudan.edu.cn (YX); ruichen@bcm.edu (RC)

Affiliation Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Competing Interests

This work was largely supported by Microsoft Research Asia with sponsorship number FY10-RES-OPP-010. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: YC YX RC WW. Performed the experiments: YC JH WC. Analyzed the data: YC YX RC. Contributed reagents/materials/analysis tools: YC JH WC WW YX RG. Wrote the paper: YC JZ YX RC. Provided data: RG.