About the Authors
- Barbara Klink
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Contributed equally to this work with: Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C. Huszthy
Affiliation Institut für Klinische Genetik, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Hrvoje Miletic
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Contributed equally to this work with: Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C. Huszthy
Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, The Gade Institute, Department of Pathology, Haukeland University Hospital, Bergen, Norway
- Daniel Stieber
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Contributed equally to this work with: Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C. Huszthy
Affiliation Centre de Recherche Public de la Santé, Luxembourg
- Peter C. Huszthy
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Contributed equally to this work with: Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C. Huszthy
Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, Department for Histology and Embryology, School of Medicine, University of Rijeka, Rijeka, Croatia
- Jaime Alberto Campos Valenzuela
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Affiliation Institut für Medizinische Informatik und Biometrie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Jörg Balss
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Affiliation Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany
- Jian Wang
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Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, Oncomatrix Research Laboratory, Department of Biomedicine, University of Bergen, Jonas Bergen, Norway
- Manja Schubert
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Affiliation Department of Clinical Medicine, Section Neurology, Haukeland University Hospital, Bergen, Norway
- Per Øystein Sakariassen
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Affiliation Department of Biomedicine, University of Bergen, Bergen, Norway
- Terje Sundstrøm
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Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway, Department of Surgical Sciences, University of Bergen, Bergen, Norway
- Anja Torsvik
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Affiliation Department of Biomedicine, University of Bergen, Bergen, Norway
- Mads Aarhus
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Affiliation Department of Neurosurgery, Oslo University Hospital, Oslo, Norway
- Rupavathana Mahesparan
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Affiliation Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway
- Andreas von Deimling
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Affiliations Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany, Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany
- Lars Kaderali
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Affiliation Institut für Medizinische Informatik und Biometrie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Simone P. Niclou
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Affiliation Centre de Recherche Public de la Santé, Luxembourg
- Evelin Schröck
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Affiliation Institut für Klinische Genetik, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
- Rolf Bjerkvig
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Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, Centre de Recherche Public de la Santé, Luxembourg
- Janice M. Nigro
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* E-mail: janice.nigro@biomed.uib.no
Affiliation Department of Biomedicine, University of Bergen, Bergen, Norway
Competing Interests
The authors have read the journal's policy and have the following conflicts: Jörg Balss and Andreas von Deimling applied for a patent on the biochemical assay for 2-hydroxyglutarate detection. All terms are being managed by the German Cancer Cover Letter Research Center in accordance with its conflict of interest policies. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. Number EP 12 157 663.1 is the number for the European patent application submitted 01 March, 2012 and entitled “Means and Methods for the Determination of (D)-2-Hydroxyglutarate (D2HG).”
Author Contributions
Conceived and designed the experiments: JMN. Performed the experiments: JMN BK HM DS PCH JACV JB JW MS TS AT. Analyzed the data: JMN BK HM DS PCH JACV JB JW TS AT AvD SPN LK ES. Contributed reagents/materials/analysis tools: PØS MA RM. Wrote the paper: JMN RB BK.