About the Authors

Laura Stappert

Contributed equally to this work with: Laura Stappert, Lodovica Borghese

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Lodovica Borghese

Contributed equally to this work with: Laura Stappert, Lodovica Borghese

borghese@uni-bonn.de (LB); brustle@uni-bonn.de (OB)

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Beate Roese-Koerner

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Sandra Weinhold

Affiliation Institute for Transplantation Diagnostics and Cell Therapeutics, University Düsseldorf, Düsseldorf, Germany

Philipp Koch

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Stefanie Terstegge

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Markus Uhrberg

Affiliation Institute for Transplantation Diagnostics and Cell Therapeutics, University Düsseldorf, Düsseldorf, Germany

Peter Wernet

Affiliation Institute for Transplantation Diagnostics and Cell Therapeutics, University Düsseldorf, Düsseldorf, Germany

Oliver Brüstle

borghese@uni-bonn.de (LB); brustle@uni-bonn.de (OB)

Affiliation Institute of Reconstructive Neurobiology, LIFE & BRAIN Center, University of Bonn and Hertie Foundation, Bonn, Germany

Competing Interests

O.B. is co-founder of and has stock in LIFE & BRAIN GmbH. The lt-NES cell technology is proprietary (DE197 56 864.4 and all derivatives), and Lt-NES® is a registered trademark of LIFE & BRAIN GmbH. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials for non-commercial purposes.

Author Contributions

Manuscript reviewing: BRK SW MU PW. Financial support: LB OB MU PW. Conceived and designed the experiments: LS LB BRK SW PW OB. Performed the experiments: LS LB BRK SW. Analyzed the data: LS LB BRK SW MU OB. Contributed reagents/materials/analysis tools: PK ST. Wrote the paper: LS LB OB.