About the Authors

Kilian Friedrich

Contributed equally to this work with: Kilian Friedrich, Christian Rupp

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Christian Rupp

Contributed equally to this work with: Kilian Friedrich, Christian Rupp

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Johannes Roksund Hov

Affiliations Norwegian PSC Research Center, Research Institute for Internal Medicine and Department of Gastroenterology, Division for Cancer, Surgery and Transplantation, Oslo University Hospital, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Niels Steinebrunner

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Karl-Heinz Weiss

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Adolf Stiehl

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Maik Brune

Affiliation Department of Internal Medicine I, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Petra Kloeters Yvonne Schaefer
Peter Schemmer

Affiliation Department of General Surgery, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Peter Sauer

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Peter Schirmacher

Affiliation Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Heiko Runz

Affiliation Institute of Human Genetics, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Tom Hemming Karlsen

Affiliations Norwegian PSC Research Center, Research Institute for Internal Medicine and Department of Gastroenterology, Division for Cancer, Surgery and Transplantation, Oslo University Hospital, Oslo, Norway, Institute of Medicine, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway

Wolfgang Stremmel

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Daniel Nils Gotthardt

Daniel.Gotthardt@med.uni-heidelberg.de

Affiliation Department of Internal Medicine IV, University Hospital of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KHW WS DNG. Performed the experiments: NS MB YS PK. Analyzed the data: KF DNG KHW JRH. Contributed reagents/materials/analysis tools: AS KF CR P. Sauer P. Schemmer P. Schirmacher JRH THK DNG. Wrote the paper: KF CR JRH HR DNG.