About the Authors

Stefano Toldo

Contributed equally to this work with: Stefano Toldo, Rachel W. Goehe

stoldo2@vcu.edu

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

Rachel W. Goehe

Contributed equally to this work with: Stefano Toldo, Rachel W. Goehe

Affiliation Department of Pharmacology and Massey Cancer, Virginia Commonwealth University, Richmond, Virginia, United States of America

Marzia Lotrionte

Affiliation Division of Cardiology, Catholic University of Sacred Heart, Rome, Italy

Eleonora Mezzaroma

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

Evan T. Sumner

Affiliation Department of Pharmacology and Massey Cancer, Virginia Commonwealth University, Richmond, Virginia, United States of America

Giuseppe G. L. Biondi-Zoccai

Affiliation Department of Medico-Surgical Sciences and Biotechnologies, “La Sapienza" University of Rome, Rome, Italy

Ignacio M. Seropian

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

Benjamin W. Van Tassell

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

Francesco Loperfido

Affiliation Division of Cardiology, Catholic University of Sacred Heart, Rome, Italy

Giovanni Palazzoni

Affiliation Division of Radiotherapy, Catholic University of Sacred Heart, Rome, Italy

Norbert F. Voelkel

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

Antonio Abbate

Affiliation Virginia Commonwealth University Pauley Heart Center and Victoria Johnson Center, Richmond, Virginia Commonwealth University, Richmond, Virginia, United States of America

David A. Gewirtz

Affiliation Department of Pharmacology and Massey Cancer, Virginia Commonwealth University, Richmond, Virginia, United States of America

Competing Interests

ML and GGLBZ have received research support from Cephalon, Rome, Italy. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ST RWG ML EM BWVT NFV AA DAG. Performed the experiments: ST RWG EM ETS IMS BWVT AA DAG. Analyzed the data: ST ML EM GGLBZ BWVT AA DAG. Wrote the paper: ST ML GGLBZ FL GP NFV AA DAG.