About the Authors

Alexa N. Bramall

Affiliations Program in Developmental Biology, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Michael J. Szego

Affiliations Program in Developmental Biology, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Laura R. Pacione

Affiliations Program in Developmental Biology, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Inik Chang

Affiliation Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Eduardo Diez

Affiliation Lady Davis Research Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada

Pedro D'Orleans-Juste

Affiliation Department of Anatomy and Cell Biology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada

Duncan J. Stewart

Affiliation The Regenerative Medicine Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada

William W. Hauswirth

Affiliation Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America

Masashi Yanagisawa

Affiliation Department of Molecular Genetics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Roderick R. McInnes

rod.mcinnes@mcgill.ca

Affiliations Program in Developmental Biology, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Lady Davis Research Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada

Competing Interests

The authors have read the journal's policy and have the following conflicts: W.W.H. and the University of Florida have a financial interest in the use of AAV therapies, and own equity in a company (AGTC Inc.) that might, in the future, commercialize some aspects of this work. As required for submission, the authors would like to add that, ‘this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.’ Additionally, there are currently no patents or patent applications relating to material pertinent to the manuscript.

Author Contributions

Editing: WH. Conceived and designed the experiments: AB RM IC. Performed the experiments: AB IC. Analyzed the data: AB RM MS LP ED. Contributed reagents/materials/analysis tools: IC MY WH PD DS. Wrote the paper: AB RM.