About the Authors

Aruna D. Balgi

Contributed equally to this work with: Aruna D. Balgi, Jun Wang

Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

Jun Wang

Contributed equally to this work with: Aruna D. Balgi, Jun Wang

Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

Daphne Y. H. Cheng

Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

Chunlong Ma

Affiliation Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America

Tom A. Pfeifer

Affiliation The Centre for Drug Research and Development, Vancouver, British Columbia, Canada

Yoko Shimizu

Affiliation The Centre for Drug Research and Development, Vancouver, British Columbia, Canada

Hilary J. Anderson

Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

Lawrence H. Pinto

Affiliation Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America

Robert A. Lamb

Affiliations Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois, United States of America, Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America

William F. DeGrado

Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

Michel Roberge

michelr@mail.ubc.ca

Affiliations Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada, The Centre for Drug Research and Development, Vancouver, British Columbia, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JW TP WFD MR. Performed the experiments: ADB JW DYHC CM YS. Analyzed the data: ADB JW TP YS LHP RAL WFD MR. Wrote the paper: ADB JW HJA WFD MR.