About the Authors

Emil Anthony T. Say

Affiliation Kittner Eye Center, University of North Carolina Hospitals, Chapel Hill, North Carolina, United States of America

Alex Melamud

Affiliation Retina Group of Washington, Washington, D.C., United States of America

Denise Ann Esserman

Affiliation Departments of Medicine, Division of General Medicine and Clinical Epidemiology and Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America

Thomas J. Povsic

Affiliation Duke Clinical Research Institute and Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

Sai H. Chavala

schavala@med.unc.edu

Affiliation Kittner Eye Center, University of North Carolina Hospitals, Chapel Hill, North Carolina, United States of America

Competing Interests

SHC has filed a patent application no. 61/471,837 entitled “Risk Analysis for Disease Development” on April 5, 2011, that relates to automated rare cell analysis in age-related macular degeneration. SHC is founder of Serrata, LLC, currently a virtual start-up company that plans to market diagnostic testing for ocular disease.

Author Contributions

Conceived and designed the experiments: SC. Performed the experiments: TJP. Analyzed the data: SC ES DE. Contributed reagents/materials/analysis tools: SC AM TJP DE. Wrote the paper: SC ES AM.