About the Authors
- Sherene Loi
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* E-mail: sherene.loi@bordet.be
Affiliation Breast Cancer Translational Research Laboratory (BCTL), Jules Bordet Institute, Brussels, Belgium
- Stefan Michiels
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Affiliation Breast Cancer Translational Research Laboratory (BCTL), Jules Bordet Institute, Brussels, Belgium
- Jose Baselga
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Affiliation Division of Hematology and Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States of America
- John M. S. Bartlett
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Affiliations Endocrine Cancer Group, University of Edinburgh Cancer Research Centre, Western General Hospital, Edinburgh, United Kingdom, Ontario Institute for Cancer Research, Toronto, Ontario, Canada
- Sandeep K. Singhal
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Affiliation Breast Cancer Translational Research Laboratory (BCTL), Jules Bordet Institute, Brussels, Belgium
- Vicky S. Sabine
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Affiliation Endocrine Cancer Group, University of Edinburgh Cancer Research Centre, Western General Hospital, Edinburgh, United Kingdom
- Andrew H. Sims
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Affiliation Edinburgh Breast Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom
- Tarek Sahmoud
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Affiliation Novartis Pharma, East Hanover, New Jersey, United States of America
- J. Michael Dixon
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Affiliation Applied Bioinformatics of Cancer Group, Edinburgh Breakthrough Unit, University of Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
- Martine J. Piccart
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Affiliation Department of Medicine, Jules Bordet Institute, Brussels, Belgium
- Christos Sotiriou
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Affiliation Breast Cancer Translational Research Laboratory (BCTL), Jules Bordet Institute, Brussels, Belgium
Competing Interests
SL and CS are named inventors on a provisional worldwide patent filed by the Université Libre de Bruxelles for the PIK3CA mutation-associated gene signature (PIK3CA-GS). TS is an employee of Novartis Pharma. All the other authors declare no conflicts of interest. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SL SM JMSB CS. Performed the experiments: SL SM. Analyzed the data: SL SM. Contributed reagents/materials/analysis tools: JB JMSB SKS VSS AHS TS JMD MJP CS. Wrote the paper: SL SM.