About the Authors

Katherine A. Abrahams

Contributed equally to this work with: Katherine A. Abrahams, Jonathan A. G. Cox

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Jonathan A. G. Cox

Contributed equally to this work with: Katherine A. Abrahams, Jonathan A. G. Cox

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Vickey L. Spivey

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Nicholas J. Loman

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Mark J. Pallen

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Chrystala Constantinidou

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Raquel Fernández

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Carlos Alemparte

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Modesto J. Remuiñán

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

David Barros

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Lluis Ballell

g.besra@bham.ac.uk (GSB); Lluis.p.ballell@gsk.com (LB)

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Gurdyal S. Besra

g.besra@bham.ac.uk (GSB); Lluis.p.ballell@gsk.com (LB)

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Competing Interests

RF, CA, MJR, DB and LB are affiliated to Diseases of the Developing World, GlaxoSmithKline: This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KAA JAGC LB DB GSB. Performed the experiments: KAA JAGC VLS CA MJR RF CC. Analyzed the data: KAA JAGC NJL GSB. Contributed reagents/materials/analysis tools: LB MJP GSB. Wrote the paper: KAA JAGC LB DB GSB.